Publications

2024

D. A. Koomson, J. H. Nicholson, A. P. S. Brogan*, and L. Aldous. “Re-assessing viologens for modern bio-electrocatalysis“. Chem. Sci., 2024, ASAP.

Y. Chen, X. Lin, X. Liu, Y. Liu, L. Bui-Le, A. K. Blakney, J. Yeow, Y. Zhu, M. M. Stevens, R. J. Shattock, R. Chen, A. P. S. Brogan*, and J. P. Hallett. “Thermally Robust Solvent-Free Liquid Polyplexes for Heat-Shock Protection and Long-Term Room Temperature Storage of Therapeutic Nucleic Acids“. Biomacromolecules, 2024, ASAP.

S. M. Meza Huaman, J. H. Nicholson, and A. P. S. Brogan. “A general route to retooling hydrolytic enzymes toward plastic degradation“. Cell Rep. Phys. Sci., 2024, 5, 101783.

2023

J. C. Brookes, E. R. Gray, C. N. Loynachan, M. J. Gut, B. S. Miller, A. P. S. Brogan, and R. A. McKendry. “Thermodynamic analysis of an entropically driven, high affinity nanobody-HIV p24 interaction“. Biophys. J., 2023, 122, 279-289

2021

A. P. S. Brogan “Preparation and application of solvent-free liquid proteins with enhanced thermal and anhydrous stabilities“. New J. Chem., 2021, 45, 6577-6585

G. Schirò, Y. Fichou, A. P. S. Brogan, R. Sessions, W. Lohstroh, M. Zamponi, G. J. Schneider, F.-X. Gallat, A. Paciaroni, D. J. Tobias, A. Perriman, and M. Weik “Diffusivelike Motions in a Solvent-Free Protein-Polymer Hybrid“. Phys. Rev. Lett., 2021, 126, 088102

C. J. Clarke, R. P. Matthews, A. P. S. Brogan and J. P. Hallett. “Controlling surface chemistry and mechanical properties of metal ionogels through Lewis acidity and basicity“. J. Mater. Chem. A, 2021, 9, 4679-4686

L. Bui-Le, A. P. S. Brogan and J. P. Hallett. “Solvent‐free liquid avidin as a step toward cold chain elimination“. Biotechnol. Bioeng., 2021, 118, 592-600

2020

L. Bui-Le, C. J. Clarke, A. Brohl, A. P. S. Brogan, J. A. J. Arpino, K. M. Polizzi and J. P. Hallett. “Revealing the complexity of ionic liquid–protein interactions through a multi-technique investigation“. Commun. Chem., 2020, 3, 55

 

A. P. S. Brogan, C. J. Clarke, A. Charalambidou, C. N. Loynachan, S. E. Youngs, J. Doutch, and J. P. Hallett. “Expanding the design space of gel materials through ionic liquid mediated mechanical and structural tuneability“. Mater. Horiz., 2020, 7, 820-826

 

2019

A. P. S. Brogan, N. Heldman, J. P. Hallett, and A. M. Belcher. “Thermally robust solvent-free biofluids of M13 bacteriophage engineered for high compatibility with anhydrous ionic liquids“. Chem. Commun., 2019, 55, 10752-10755

 

2018

A. P. S. Brogan, L. Bui-Le, and J. P. Hallett. “Non-aqueous homogenous biocatalytic conversion of polysaccharides in ionic liquids using chemically modified glucosidase“. Nat. Chem., 2018, 10, 859-865.

[Featured in Nature’s Green Chemistry Collection]

 

2016

A. P. S. Brogan, and J. P. Hallett. “Solubilizing and Stabilizing Proteins in Anhydrous Ionic Liquids through Formation of Protein–Polymer Surfactant Nanoconstructs“. J. Am. Chem. Soc., 2016, 138, 4494-4501.

 

2014

A. P. S. Brogan, R. B. Sessions, A. W. Perriman, and S. Mann. “Molecular Dynamics Simulations Reveal a Dielectric-Responsive Coronal Structure in Protein–Polymer Surfactant Hybrid Nanoconstructs“. J. Am. Chem. Soc., 2014, 136, 16824-16831.

 

A. P. S. Brogan, K. P. Sharma, A. W. Perriman, and S. Mann. “Enzyme activity in liquid lipase melts as a step towards solvent-free biology at 150 °C“. Nat. Commun., 2014, 5, 5058.

 

K. P. Sharma, Y. Zhang, M. R. Thomas, A. P. S. Brogan, A. W. Perriman, and S. Mann. “Self-Organization of Glucose Oxidase–Polymer Surfactant Nanoconstructs in Solvent-Free Soft Solids and Liquids“. J. Phys. Chem. B, 2014, 118, 11573-11580.

2013

K. P. Sharma, K. Bradley, A. P. S. Brogan, S. Mann, A. W. Perriman, and D. J. Fermin. “Redox Transitions in an Electrolyte-Free Myoglobin Fluid“. J. Am. Chem. Soc, 2013, 135, 18311-18314.

 

A. P. S. Brogan, K. P. Sharma, A. W. Perriman, and S. Mann. “Isolation of a Highly Reactive β-Sheet-Rich Intermediate of Lysozyme in a Solvent-Free Liquid Phase“. J. Phys. Chem. B, 2013, 117, 8400-8407.

 

2012

F.-X. Gallat, A. P. S. Brogan, Y. Fichou, N. McGrath, M. Moulin, M. Härtlein, J. Combet, J. Wuttke, S. Mann, G. Zaccai, C. J. Jackson, A. W. Perriman, and M. Weik. “A Polymer Surfactant Corona Dynamically Replaces Water in Solvent-Free Protein Liquids and Ensures Macromolecular Flexibility and Activity“. J. Am. Chem. Soc., 2012, 132, 13168–13171.

 

A. P. S. Brogan, G. Siligardi, R. Hussain, A. W. Perriman, and S. Mann. “Hyper-thermal stability and unprecedented re-folding of solvent-free liquid myoglobin“. Chem. Sci., 2012, 3, 1839–1846.

 

2010

A. W. Perriman, A. P. S. Brogan, H. Cölfen, N. Tsoureas, G. R. Owen, and S. Mann. “Reversible dioxygen binding in solvent-free liquid myoglobin“. Nat. Chem., 2010, 2, 622–626.

 
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